• Reconstruction of signaling pathways using
a variety of different reporter assays.
• Drug Target Discovery/ Assay Development by
overexpression and inhibition of expression with RNAi
• Enzyme/Promoter co-expression in hepatic cell
lines
• Evaluate functional consequences of SNP or
splice variants
• Functional assays for multisubunit drug targets
(ion channels, complex kinases and transcription factors)
• Protein-protein interactions in vivo using
FRET and bi-molecular fluorescence
